The Chest of a Thousand Grogs is a cursed Treasure Chest that can be found within a Voyage, Quest or sunken ship in Sea of Thieves.  

Carrying the chest will make the player immediately drunk, causing their character to stumble and the surrounding view to sway in such a way that it becomes harder to navigate. The player will also hear music and laughter as though they were in a tavern. Dropping the chest causes the effect to end.